New Drug Targets Bone Disease That Causes Hearing Loss
The drug LGK974, which inhibits the Wnt signaling pathway, shows promise in reversing excessive bone growth in sclerosteosis.
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Search Results for: drug
Sensorion Enrolls Last Patient in Clinical Trial of Drug to Prevent Cisplatin-Induced Ototoxicity
Sensorion has completed patient enrollment for its Phase 2a NOTOXIS trial, evaluating SENS-401’s potential to prevent Cisplatin-induced ototoxicity.
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Sound Pharma Gets Positive Results from Meniere’s Disease Drug Clinical Trial
Sound Pharmaceuticals’ Phase 3 trial of an anti-inflammatory drug for Meniere’s disease showed significant improvements in hearing loss.
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New Drug Delivery System Developed for Chemo-Induced Hearing Loss
The novel drug delivery system uses hydrogels and nanoparticles to protect against hearing loss caused by the chemotherapy drug cisplatin.
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Sensorion Gets Positive Recommendation for Clinical Trial of Drug Candidate for Cisplatin-Induced Ototoxicity
Sensorion was recommended to continue the study of a drug candidate for the prevention of Cisplatin-Induced Ototoxicity (CIO).
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Study Details Chemo Drug Effect on Hearing Loss in Cancer Survivors
A study found that 78% of testicular cancer survivors treated with cisplatin-based chemotherapy experience significant hearing difficulties.
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Audion Therapeutics Publishes Trial Details on Drug Treatment for Sensorineural Hearing Loss
The Phase I part of the study confirmed the safety and tolerability of a dose of 250 microgram of Gamma Secretase Inhibitor LY3056480.
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Could a Drug Help Preserve Hearing Health?
Scientists from the University of California San Francisco (UCSF) identified a gene that links deafness to cell death in the inner ear.
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Scientists Create Drug-like Cocktail to Regenerate Hair Cells
Scientists at Mass Eye and Ear may have developed a solution for hearing loss by creating a drug-like cocktail that regenerated hair cells in a mouse model.
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Memory Treatment Centers One of the First Medical Organizations to Offer the Alzheimer’s Drug Leqembi
Memory Treatment Centers (MTC) became amongst the very first healthcare organizations within the United States to successfully begin administering Leqembi (lecanemab-irmb)to qualified patients at its facilities.
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Sensorion Announced Orphan Drug Designation for OTOF-GT
Sensorion (FR0012596468 – ALSEN) a clinical-stage biotechnology company which specializes in the development of novel therapies to restore, treat, and prevent within the field of hearing loss disorders, announced that the US Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) to OTOF-GT, Sensorion’s lead gene therapy program, intended for the treatment of otoferlin gene-mediated hearing loss. Sensorion is on track to file a Clinical Trial Application for OTOF-GT in the first half of 2023.
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FDA Approves Fennec Pedmark Ototoxicity Drug
Fennec Pharmaceuticals Inc. (NASDAQ: FENC; TSX: FRX), a specialty pharmaceutical company, announced that the US Food and Drug Administration (FDA) has approved Fennec Pedmark (sodium thiosulfate injection) to reduce the risk of ototoxicity associated with cisplatin in pediatric patients one month of age and older with localized, non-metastatic solid tumors. This approval reportedly makes Pedmark “the first and only treatment approved by the FDA in this area of significant unmet medical need.”
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Sensorion Announces Disappointing Results from SSNHL Drug Trial
The company reports that SENS-401 was “safe and well tolerated, however, it did not meet the primary endpoint of 15 dB, a significant improvement in pure tone audiometry (PTA, dB) in the affected ear from baseline in comparison to placebo at the end of the four-week treatment period.”
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U of Pittsburgh Researcher Working on Tinnitus Drug
The drug they’ve been focusing on, called RL-81, would be used soon after tinnitus develops, and recent research indicates it could remain effective much longer than they first expected.
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Chemotherapy Drug More Harmful to Young Children
A chemotherapy drug known to cause hearing loss in children is more likely to do so the earlier in life children receive it, new University of British Columbia (UBC) research published on its website has found.
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